Family name De Stefano (Destefano 
, De Stefano ) , worldwide, is a common cognomen. The last name De Stefano is habitual in Italy, where it is quite a common surname, Argentina, where it is quite a rare surname, and the United States.
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| De Stefano, Destefano | Brazil, Italy, Argentina, United States, France |
Di, Di Stefano, Stefano, and Ди Стефано
| tommaso de stefano Roman Catholic archbishop (b. 1853) |
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| vincenzo de stefano IT (b. 1861) |
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marcello de stefano Italian painter, IT (b. 1929) |
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| felice de stefano IT (b. 1889) |
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| marino de stefano IT (b. 1903) |
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alessandra de stefano Italian journalist and writer, IT (b. 1966) |
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maryse de stefano (b. 1965) |
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| armando de stefano Italian painter, IT (b. 1926) |
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| giulio de stefano sailor, IT (b. 1929) |
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| carlo de stefano Italian civil servant, IT (b. 1943) |
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| paolo de stefano Italian criminal (1943-1985), IT (b. 1943) |
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| giorgio de stefano Italian criminal, IT (b. 1948) |
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| gennaro de stefano Italian journalist and writer (1951-2008), IT (b. 1951) |
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| silvana de stefano Sculptor and architect, IT (b. 1954) |
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| giorgio de stefano IT (b. 1948) |
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